I believe that facing the bases loaded in the seventh against the #3 hitter is more stressful and more important than pitching with the bases empty in the ninth against the 7-8-9 batters. But these are all contrived generalities.
Personally, I like that thought is being applied, not just using the same cookie-cutter formula in every situation.
But of course, there will still be failures as well as successes. You just hope to increase the latter and decrease the former over the long haul.