St. Louis Cardinals Announce 2021 Regular Season Schedule

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St. Louis Cardinals press release

The St. Louis Cardinals, in conjunction with Major League Baseball’s league-wide release, today (Thursday, July 9) announced their 2021 regular season schedule. The home opener is set for Thursday, April 8, against Milwaukee as part of a six-game home stand with the Brewers (April 8, 10-11) and Washington (April 12-14).

The Cardinals will open the 2021 season on the road with a three-game series at Cincinnati beginning on Thursday, April 1, followed by a three-game series at Miami (April 5-7).

Among the key home dates for 2021 are a pair of three-game weekend series visits by the Chicago Cubs on May 21-23 and to conclude the regular season on October 1-3. The Cubs will also visit St. Louis for a four-game series July 19-22. Additionally, the game against the Milwaukee Brewers in St. Louis on Saturday, April 10, will mark the 15th anniversary of the first game played at Busch Stadium III (also against the Brewers).

The 2021 season will feature 26 home series and 26 road series, including 13 weekend series at Busch Stadium: April 8, 10-11 vs. Milwaukee, April 23-25 vs. Cincinnati, May 7-9 vs. Colorado, May 21-23 vs. Chicago Cubs, June 3-6 vs. Cincinnati, June 24-27 vs. Pittsburgh, July 16-18 vs. San Francisco, July 30-August 1 vs. Minnesota, August 6-8 vs. Kansas City, August 20-22 vs. Pittsburgh, September 10-12 vs. Cincinnati, September 17-19 vs. San Diego, and October 1-3 vs. Chicago Cubs.

The Cardinals 20-game interleague schedule will feature a pair of three-game home-and-home series with in-state rival Kansas City on consecutive weekends (August 6-8 at Busch Stadium & August 13-15 at Kansas City), marking the first time the Cardinals have hosted a three-game weekend series against the Royals since 2015. The interleague schedule also features a pair of two-game home-and-home series against the Cleveland Indians (June 8-9 at Busch Stadium & July 27-28 at Cleveland) and the Detroit Tigers (June 22-23 at Detroit & August 24-25 at Busch Stadium). Additionally, the Redbirds will host a three-game interleague series versus the Minnesota Twins (July 30-August 1) and travel to Chicago for a three-game interleague series against the White Sox (May 24-26).

The Cardinals are scheduled to play 41 of their 81 home games before the July 12-14 All Star Break, playing 13 home games in April, 12 in May, 16 in June, 9 in July, 15 in August, and 16 in September/October. The club is scheduled to host holiday games on Mother’s Day (May 9 vs. Colorado) and Labor Day (September 6 vs. Los Angeles Dodgers).

The Cardinals longest home stand of the 2021 consists of nine games (July 30-August 8) with three games against each of the Twins, Atlanta Braves, and Royals. Their longest road trip consists of two 10-game trips from May 24-June 2 and before the All-Star Break from July 1-11. The team has two stretches that will see them play 17 consecutive games without a day off from April 23-May 9 and May 21-June 6.

The Cardinals will make future announcements regarding game times, ticket pricing and ticket availability for the 2021 season. The complete 2021 regular season schedule can be viewed at


April 8, 10-11 vs. Milwaukee
April 12-14 vs. Washington
April 23-25 vs. Cincinnati
April 26-29 vs. Philadelphia
May 3-6 vs. New York Mets
May 7-9 vs. Colorado
May 18-19 vs. Pittsburgh
May 21-23 vs. Chicago Cubs
June 3-6 vs. Cincinnati
June 8-9 vs. Cleveland
June 14-16 vs. Miami
June 24-27 vs. Pittsburgh
June 28-30 vs. Arizona
July 16-18 vs. San Francisco
July 19-22 vs. Chicago Cubs
July 30-August 1 vs. Minnesota
August 3-5 vs. Atlanta
August 6-8 vs. Kansas City
August 17-19 vs. Milwaukee
August 20-22 vs. Pittsburgh
August 24-25 vs. Detroit
September 6-9 vs. Los Angeles Dodgers
September 10-12 vs. Cincinnati
September 17-19 vs. San Diego
September 28-30 vs. Milwaukee
October 1-3 vs. Chicago Cubs

Full schedule – Grid view

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